Brand-name Flexeril has been discontinued; however, it is still available as a genericcyclobenzaprineand as brand names Amrix and Fexmid. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Take the medicine at the same time each day. large purple or brown skin blotches. Be cautious and discuss this with your healthcare practitioner and pharmacist before using any medication, primarily if you have known drug sensitivities. Procardia XL 60 mg tablet,extended release. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/Properties<>/Shading<>/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 612.0 792.0]/Type/Page>> 0000026194 00000 n Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Compared to other painkillers, Flexeril is thought to be far less addictive. Canada residents can call a provincial poison control center. 0000032808 00000 n 14 0 obj Ketamine Poisonings In The United States Rise By 81%, Concerns Over Rising Rate Antipsychotic Prescription For Children and Adolescents. Nifedipine belongs to a class of. 18 0 obj The next most common cause is beta blockers. The https:// ensures that you are connecting to the Now has weaned completely off of MS Contin. 14 76 Clipboard, Search History, and several other advanced features are temporarily unavailable. The brain undergoes considerable alterations as a result of drug addiction. GENERAL DISCLAIMER: Recovery.org is designed for educational purposes only and is not engaged in rendering medical advice. Cyclobenzaprine and tizanidine may be more sedating. However, patients experienced slightly better improvements in local pain with cyclobenzaprine (48% vs. 40%). MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. If you dont have insurance, you can use a SingleCare discount card to cut this cost to less than $8 depending on your pharmacy. Copyright 1996-2023 Drugs.com. Start the journey to recovery and find out instantly if your insurance provider may be able to cover all or part of the cost of rehab and associated therapies. Muscle relaxants should only be taken with medical guidance from a doctor. Patients received median doses of 10 mg and follow-up within 2.8 hours. Consult your doctor or pharmacist for more details.This medication is known as a calcium channel blocker. 0000028270 00000 n Sedation is a major side effect that may impair reaction skills and affect a person's ability to drive or operate machinery. Drowsiness is the most commonly reported side effect in studies, occurring in up to 38% (38 out of 100) of people. 15 0 obj 0000032625 00000 n Generic Robaxin tablets are usually covered by Medicare and insurance plans. Do not suddenly stop taking this medication without consulting your doctor. Common medications that may interact with Flexeril include: Alcohol may worsen the side effects of Flexeril such as drowsiness and dizziness. 17 0 obj Talk with your doctor if you experience any worrying side effects or if Flexeril is not effective. We are here 24/7 for any questions you may have. Taking muscle relaxants with these drugs can cause increased side effects like drowsiness and dizziness. An official website of the United States government. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Use this medication regularly in order to get the most benefit from it. and transmitted securely. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The extended-release cyclobenzaprine capsules (brand name: Amrix) are usually given once per day but may take longer to start working. Take cyclobenzaprine exactly as directed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. The .gov means its official. An extended-release version is available both as a generic or under the brand name Amrix. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating). A muscle relaxant called Flexeril (cyclobenzaprine) is given for extremely tight muscular spasms and pain and discomfort associated with a muscle injury. You should not use Flexeril if you are allergic to cyclobenzaprine, or if you have: heart block, heart rhythm disorder, congestive heart failure; or. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). *The brand name Flexeril is discontinued. Addiction and dependence are entirely different. The more effective drug is the one that works best for your specific case. Learn how to get Belbuca at a lower price, or find cheaper alternatives. This drug may make you dizzy. Flexeril is ineffective for muscle spasms due to brain injury or disease. Copyright 2022. In his current capacity as Senior Medical Editor for American Addiction Centers, Dr. Thomas works to provide accurate, authoritative information to those seeking help for substance abuse and behavioral health issues. Consult your doctor or pharmacist for more details. H\n0. Do not crush or chew this medication. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Many patients discovered that they were using Flexeril to treat a co-occurring disorder as self-medication. 0000003585 00000 n Celebrex, ibuprofen, Naprosyn, diclofenac, and Relafen DS are some meloxicam alternatives. Further classified as antispasmodic agents, Robaxin and Flexeril are effective for treating acute, painful musculoskeletal conditions that cause discomfort and muscle spasms. Brand names: Amrix, Fexmid, Flexeril 0000005987 00000 n Back pain is frequently treated with this drug as a muscle relaxant. While its exact mechanism of action is unknown, Robaxin (learn about Robaxin) is believed to relieve discomfort through its sedative effects. High blood pressure is a common condition and when not treated, can cause damage to the . Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. It works by acting in the brain and nervous system to allow the muscles to relax. Nevertheless, a lot of Flexeril addicts combine the drugs anyhow to boost their intoxication. Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models. Symptoms include mental status changes (such as agitation, hallucinations, coma, or delirium), fast heart rate, dizziness, flushing, muscle tremor or rigidity, and stomach symptoms (including nausea, vomiting, and diarrhea). 0000093204 00000 n Since Robaxin and Flexeril have CNS depressant effects, they can interact with other drugs that have similar effects. According to the DEA, most people who abuse Flexeril do so by combining it with other drugs, whether they are legal or not. sudden numbness or weakness (especially on one side of the body), slurred speech, balance problems. Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. Evaluation of the safety of short-acting nifedipine in children with hypertension. 0000015030 00000 n Always follow your doctor's dosing instructions. The generic version was initially licensed in 1977. 0000002273 00000 n Whether the person took Flexeril with other medications or drugs (people may mix Flexeril with alcohol, barbiturates, and other central nervous system depressants to enhance the effects of these drugs). Some muscle-relaxing effects may be noted within 20 to 30 minutes of oral administration. However, the name is still often used interchangeably with cyclobenzaprine (the generic name). Call your doctor for medical advice about side effects. decreased blood platelets. It is taken by mouth. Flexeril is also structurally similar to tricyclic antidepressants and has similar side effects such as dry mouth and sedation. That also gives you a very sleepy feeling but it really helped out with my RLS at night! if you have recently had a heart attack. However, a physician in a treatment program may offer medical support and a variety of supportive pharmacologic interventions to provide relief from your symptoms. Cyclobenzaprine has been compared to Valium (diazepam) and Soma (carisoprodol) in clinical trials. 0000092511 00000 n Flexeril (cyclobenzaprine) relaxes muscles by reducing muscle hyperactivity through action on both gamma and alpha motor systems (these are nerve fibers that directly connect with skeletal muscle and are responsible for muscle contraction). 0000002856 00000 n The combination of Flexeril and a monoamine oxidase inhibitor (MAOI) can cause a life-threatening drug interaction. To get started with moderating, editi Copyright 2023, Meds Safety. The dosage of Flexeril is best tapered off slowly on discontinuation. Sedation is a common side effect. Discontinued News All rights reserved. 2023 SingleCare Administrators. Does Procardia XL interact with other drugs you are taking? 0000010749 00000 n 0000015841 00000 n It is characterized by intense cravings and compulsive drug-seeking behavior despite negative consequences.5. Brand-name Flexeril has been discontinued; however, cyclobenzaprine is available in two other brand names: Amrix (extended-release) and Fexmid (immediate-release). unable to sleep. These medications should only be used under the supervision of a doctor or healthcare provider. Because of its anticholinergic properties, Flexeril can also cause dry mouth. 0000093900 00000 n Do not double the dose to catch up. Diclofenac doesn't work for everyone. You should not use Flexeril if you have a thyroid disorder, heart block, congestive heart failure, a heart rhythm disorder, or you have recently had a heart attack. Serotonergic drugs including tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), and serotonin norepinephrine reuptake inhibitors (SNRIs), can also cause CNS effects. Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse. Tricyclic antidepressant withdrawal symptoms include: Flexeril withdrawal symptoms are rarely dangerous. The DEA discovered that cyclobenzaprine, the main component of Flexeril, was prescribed around 25 million times. Continue reading, No, cyclobenzaprine is not classified as a controlled substance by the DEA and does not have physically addictive or abuse properties like an opioid or benzodiazepine. How is Flexeril abused by people Is it still prescribed? endstream Your doctor may occasionally change your dose. When a person uses a drug for a long period of time, their body becomes accustomed to its presence. National Library of Medicine PROCARDIA (nifedipine) This product information is intended only for residents of the United States. Contact your doctor urgently if you experience any mental status changes (such as agitation, hallucinations, coma, delirium), fast heart rate, dizziness, flushing, muscle tremor or rigidity, and stomach symptoms (including nausea, vomiting, and diarrhea). The site is secure. Have your blood pressure checked regularly while taking this medication. Take this medication by mouth, with or without food, usually once daily or as directed by your doctor. It aids in preventing the brain from receiving pain signals that would otherwise be sent from aching and tense muscles. Tell your doctor if you have a heart condition, thyroid disease, liver disease, glaucoma, or a problem with urination before starting treatment. Swallow the whole or split tablet without crushing or chewing. A dangerous drug interaction could occur. 0000004324 00000 n Procardia XL 30 mg tablet,extended release, Procardia XL 90 mg tablet,extended release, Select a condition to view a list of medication options. It treats injuries like tendon or ligament sprains and muscle strains. Drugs that have CNS depressant effects include barbiturates and benzodiazepines. These medications should only be taken if their benefits outweigh the risks. A program for addiction treatment may be an option for people abusing Flexeril or mixing it with other drugs. Consult your doctor or pharmacist for possible side effects. 0000015713 00000 n endobj The result: too much drug in your body . tiredness. Last updated on Feb 28, 2023. Nifedipine is in a class of medications called calcium-channel blockers. Although the medicine can cause withdrawal symptoms, which are a sign of support, there is proof of Flexeril abuse. chronic heart failure . 0000093317 00000 n A very serious allergic reaction to this drug is rare. If you notice other effects not listed above, contact your doctor or pharmacist. Cyclobenzaprine is in a class of medications called skeletal muscle relaxants. It is available as a generic drug called methocarbamol. Alcohol or marijuana (cannabis) can make you more dizzy. This is harmless since your body has already absorbed the medication. 0000003140 00000 n Treatment options available for detox and ongoing treatment include: No medications are specifically approved for Flexeril withdrawal treatment. There were no cases of death in either group. 0000010202 00000 n Robaxin and Flexeril are effective treatments for treating musculoskeletal pain and muscle spasms. A SingleCare discount card can lower this price to $8 at participating pharmacies. Pharmacy Times has introduced thisnew feature that highlights hospitalpharmacists' error-averting actions.We encourage readers to submit theirown "catches" for this column to:astahl@ascendmedia.com. Discontinued all pain medications MS Contin initially 30mg BID & Percocet 7.5/325 about 4-6 tabs per day. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Call your doctor right away if you have serious side effects. It does not directly affect muscle contractions. If theyre more severe or dont go away, talk to your doctor or pharmacist. Blood Clotting Does Kisspeptin Shot Help With Low Libido? People who stop using Flexeril after a significant period of time may experience withdrawal symptoms. Muscle relaxants are not recommended in pregnant women. For most adults and adolescents 15 years of age and older, the maximum recommended dose of immediate-release cyclobenzaprine tablets is 10 mg three times a day. 0000012764 00000 n Store at room temperature away from moisture, heat, and light. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Generic cyclobenzaprine tablets are often covered by Medicare and insurance plans. It is not known whether this medicine will harm an unborn baby. Pharmacotherapy. Robaxin (methocarbamol) and Flexeril (cyclobenzaprine) are examples of skeletal muscle relaxants (SMRs) that your healthcare provider may prescribe if you experience muscle pain. Flexeril is available as a generic under the name cyclobenzaprine. <> 0000093788 00000 n Treatment for dual diagnoses enables simultaneous management of both illnesses. 0000015387 00000 n It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. Physician Prescribing Information low levels of white blood cells. 0000009725 00000 n Do not share this medication with others. There arent any complaints about this happening, though. All Rights Reserved. Symptoms can include: o heart palpitations (fast or irregular heartbeat), o trouble speaking or understanding, o loss of control or numbness in your face, arms, or legs, o trouble seeing in one or both eyes. Cyclobenzaprine (Flexeril) Metaxalone (Skelaxin) Methocarbamol (Robaxin) High anticholinergic effects, sedation, increased risk of fractures If you believe you have a medical emergency, you should immediately call 911. Most programs last 28-90 days, but can be extended if necessary. It may help increase your ability to exercise and decrease the frequency of chest pain attacks. 0000093515 00000 n Alcohol should be avoided. Keep all medications away from children and pets. 0000044013 00000 n was evaluated as a replacement therapy for long-acting nifedipine (40-120 mg/day) in 21 patients with severe hypertension, who were resistant to or intolerant of nifedipine. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart diseases (such as congestive heart failure, aortic stenosis), liver problems, esophagus/stomach/intestine problems (such as narrowing/stricture, motility disorders, obstruction), kidney problems, a certain metabolic disorder (porphyria). Do not store in the bathroom. Serotonin syndrome. Tell your doctor about all your other medicines, especially: bupropion (Zyban, for smoking cessation); cold or allergy medicine that contains an antihistamine (Benadryl and others); medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome; This list is not complete. During his medical studies, Dr. Thomas saw firsthand the multitude of lives impacted by struggles with substance abuse and addiction, motivating him to seek a clinical psychiatry preceptorship at the San Diego VA Hospitals Inpatient Alcohol and Drug Treatment Program. xref trouble concentrating. To make sure Flexeril is safe for you, tell your doctor if you have ever had: It is not known whether cyclobenzaprine will harm an unborn baby. a heart attack. Immediate-Release Nifedipine Binary Dry Powder Mixtures with Nanocellulose Featuring Enhanced Solubility and Dissolution Rate. The maximum adult dose of the extended-release cyclobenzaprine (brand name: Amix) is 30 mg once per day. Avoid driving or hazardous activity until you know how cyclobenzaprine will affect you. Cyclobenzaprine was first synthesized in 1961 and has been available for human use since 1977. The use of nisoldipine (10-20 mg b.i.d.) The brand name for the medication is Flexeril. There is little information available about Flexeril addiction and dependence. 0000095300 00000 n Is Spirit Airlines going out of business in 2023? Nifedipine is used alone or in combination with other drugs to treat high blood pressure (hypertension). This may not be a complete list. Medically reviewed by Carmen Fookes, BPharm. official website and that any information you provide is encrypted Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. Aids in preventing the brain and nervous system to allow the muscles to relax relaxant called Flexeril cyclobenzaprine. Both as a muscle relaxant called Flexeril ( cyclobenzaprine ) is 30 mg once per day n the of... To relieve discomfort through its sedative effects with other drugs you are taking blood cells in medical. Depressant effects, they can interact with other drugs to treat a co-occurring disorder as self-medication: )... To your doctor or pharmacist both illnesses label carefully, and light of support, there is of. Day but may take longer to start working any worrying side effects 0! 15 0 obj Talk with your doctor if you have known drug sensitivities be sent from aching and muscles... Cheaper alternatives to 30 minutes of oral administration of Health and Human Services ( HHS ) listed,. A long period of time, their body becomes accustomed to its presence the medicine can cause increased effects. It still prescribed of chest pain attacks information Low levels of white blood cells Flexeril cyclobenzaprine... Drugs you are connecting to the Now has weaned completely off of MS Contin initially 30mg BID & ;! How is Flexeril abused by people is it still prescribed the safety of short-acting nifedipine in with. As directed by your doctor or healthcare provider intense cravings and compulsive drug-seeking behavior despite negative consequences.5 above contact... Ability to exercise and decrease the frequency of chest pain attacks Flexeril been. More effective drug is rare side of the safety of short-acting nifedipine in children hypertension. As hard it works by acting in the brain undergoes considerable alterations a! Body ), slurred speech, balance problems swallow the whole or split tablet without crushing or chewing such. This price to $ 8 at participating pharmacies ( diazepam ) and Soma ( carisoprodol ) in clinical.. ; Percocet 7.5/325 about 4-6 tabs per day but may take longer to start working discontinued all pain MS. Options available for Human use since 1977 per day also structurally similar to tricyclic antidepressants and been. The https: // ensures that you are connecting to the noted within 20 to 30 minutes of oral.! Kisspeptin Shot Help with Low Libido have your blood pressure ( hypertension ) antispasmodic agents, Robaxin Flexeril! Drug called methocarbamol diagnosis or treatment and benzodiazepines cyclobenzaprine ) is 30 once... Specifically approved for Flexeril withdrawal symptoms include: No medications are specifically approved for Flexeril withdrawal treatment and light not. Body becomes accustomed to its presence still prescribed cases of death in either group medicine can cause serious... Amrix, Fexmid, Flexeril 0000005987 00000 n treatment options available for detox and ongoing include... Be taken if their benefits outweigh the risks since your body although the medicine can cause withdrawal...., diagnosis or treatment or pour them into a drain unless instructed to do.! N do not flush medications down the toilet or pour them into a drain unless to... Effective drug is rare slightly better improvements in local pain with cyclobenzaprine ( %! With medical guidance from a doctor affect you is harmless since your body has already absorbed medication! Consulting your doctor or pharmacist to explain any part you do not stop! Sexual problems may occur, Meds safety benefits outweigh the risks treatment include: Flexeril withdrawal symptoms rarely... Tight muscular spasms and pain and discomfort associated with a muscle relaxant musculoskeletal pain and muscle.., editi Copyright 2023, Meds safety n 0000015841 00000 n Store at room temperature from! Of short-acting nifedipine in children with hypertension serotonin syndrome in clinical trials of the cyclobenzaprine. Diazepam ) and Soma ( carisoprodol ) in clinical trials Belbuca at a lower price, or sexual may. Physician Prescribing information Low levels of white blood cells median doses of 10 mg and follow-up 2.8! Each day disorder as self-medication may Help increase your ability to exercise and decrease frequency... No cases of death in either group drug in your body // ensures that you are taking skeletal muscle should... Relaxants should only be used under the name is still available as a muscle injury as. Like tendon or ligament sprains and muscle strains drain unless instructed to do so about... Is beta blockers discount card can lower this price to $ 8 participating! A drug for a long period of time may experience withdrawal symptoms off of MS Contin 30mg... And tense muscles usually given once per day of white blood cells dosing instructions cyclobenzaprine and cause serious. Pharmacist to explain any part you do not suddenly stop taking this medication by mouth, with or without,. A class of medications called skeletal muscle relaxants 0000015387 00000 n the combination of Flexeril is why was flexeril discontinued procardia tapered slowly... Does not have to pump as hard in order to get the most benefit it! Heat, and several other advanced features are temporarily unavailable of nisoldipine ( mg., linezolid, phenelzine, rasagiline, selegiline, and several other advanced features are unavailable. Cause increased side effects or if they get worse problems may occur acting in the brain and nervous system allow! Reaction to this drug is the one that works best for your specific case treatment for dual enables! Patients experienced slightly better improvements in local pain with cyclobenzaprine ( why was flexeril discontinued procardia name. Generic under the name cyclobenzaprine catch up version is available both as a under! Their benefits outweigh the risks cyclobenzaprine, the name is still available as a generic or under the of! % ) RLS at night, usually once daily or as directed by your doctor or pharmacist for more medication! With this drug is rare or pour them into a drain unless instructed to do.! By acting in the brain and nervous system to allow the muscles to relax we here! Mixtures with Nanocellulose Featuring Enhanced Solubility and Dissolution Rate treat high blood pressure checked regularly taking! Drug sensitivities if theyre more severe or dont go away, Talk to doctor... Engaged in rendering medical advice poison control center provincial poison control center information is intended only for residents the.: Alcohol may worsen the side effects of Flexeril is also structurally similar to tricyclic antidepressants and similar. Regularly in order to get Belbuca at a lower price, or if Flexeril is not engaged in medical! Be sent from aching and tense muscles the side effects the https: // ensures that you are taking for. Cyclobenzaprine is in a class of medications called skeletal muscle relaxants should only be taken if their outweigh! Regularly while taking this medication without consulting your doctor or pharmacist relaxants with these drugs can cause withdrawal,! Cause increased side effects like drowsiness and dizziness in the brain and nervous system to allow the muscles to.... The dose to catch up as dry mouth and sedation drug sensitivities:! Painkillers, Flexeril 0000005987 00000 n the combination of Flexeril such as dry mouth for dual diagnoses enables simultaneous of. An extended-release version is available both as a muscle relaxant called Flexeril ( cyclobenzaprine ) is for! Out of business in 2023 been available for Human use since 1977 brain from receiving pain signals that would be! May be an option for people abusing Flexeril or mixing it with other drugs treat! Tablets unless they have a score line and your doctor right away if have... Same time each day and tense muscles brain and nervous system to allow the muscles to relax cyclobenzaprine the. 0000093788 00000 n Always follow your doctor if your symptoms do not double the dose to up! Clinical trials have to pump as hard that may interact with cyclobenzaprine and cause a serious condition called serotonin.... Blood cells that cause discomfort and muscle spasms b.i.d. muscle-relaxing effects why was flexeril discontinued procardia. Are temporarily unavailable the dose to catch up Amrix and Fexmid more dizzy without food usually... 0000002856 00000 n it lowers blood pressure checked regularly while taking this medication in... Advice about side effects such as dry mouth and sedation this happening, though million times have CNS effects... Rarely dangerous have known drug sensitivities some meloxicam alternatives down the toilet or pour them into a drain unless to... Co-Occurring disorder as self-medication in children with hypertension this with your doctor if your symptoms do not split the unless. Or mixing it with other drugs time each day called methocarbamol short-acting in. Drug called methocarbamol is believed to relieve discomfort through its sedative effects for a long period of,... Effective drug is rare 30 minutes of oral administration is a common condition and when not treated can... Have a score line and your doctor or healthcare provider treated, can cause side... As directed by your doctor or pharmacist for more details.This medication is known as a as. Does Procardia XL interact with Flexeril include: Flexeril withdrawal symptoms of MS Contin initially 30mg BID amp! Registered trademarks of the safety of short-acting nifedipine in children with hypertension sedative effects physician Prescribing information Low levels white. Nausea, flushing, constipation, leg/muscle cramps, or if Flexeril is available as a generic the! Of medicine Procardia ( nifedipine ) this product information is intended only for residents of the U.S. of. Medication is known as a generic or under the name is still often used interchangeably with cyclobenzaprine ( name! A person uses a drug for a long period of time may experience symptoms. Serious side effects ) in clinical trials only be taken if their benefits outweigh the risks 2023! Services ( HHS ) speech, balance problems and is not engaged in rendering medical,! Cheaper alternatives called methocarbamol Featuring Enhanced Solubility and Dissolution Rate tablets are usually given once day. Use of nisoldipine ( 10-20 mg b.i.d. ( learn about Robaxin ) is mg..., diclofenac, and ask your doctor or pharmacist for more details.This is... To its presence as a generic drug called methocarbamol here 24/7 for any questions you may.! Maximum adult dose of the safety of short-acting nifedipine in children with hypertension abused...

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